Autoimmunity caused by host cell protein-containing viruses
نویسندگان
چکیده
منابع مشابه
B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C δ.
Primary B-cell disorders comprise a heterogeneous group of inherited immunodeficiencies, often associated with autoimmunity causing significant morbidity. The underlying genetic etiology remains elusive in the majority of patients. In this study, we investigated a patient from a consanguineous family suffering from recurrent infections and severe lupuslike autoimmunity. Immunophenotyping reveal...
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To explain the pathogenesis of autoimmunity, we hypothesize that following an infection the immune response spreads to tissue-specific autoantigens in genetically predisposed individuals eventually determining progression to disease. Molecular mimicry between viral and self antigens could, in some instances, initiate autoimmunity. Local elicitation of inflammatory cytokines following infection ...
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ژورنال
عنوان ژورنال: Medical Microbiology and Immunology
سال: 1994
ISSN: 0300-8584,1432-1831
DOI: 10.1007/bf00194172